ASSOCIATION OF VITAMIN D RECEPTOR (VDR) GENE POLYMORPHISMS WITH PHYSICAL PERFORMANCE IN ELITE ATHLETES

Authors

  • Avezova M. Z., Rakhimova N.M., Kurganov S.K. Republican Scientific and Practical Center of Sports Medicine under the National Olympic Committee of Uzbekistan, Tashkent. Institute of Biophysics and Biochemistry of the Mirzo Ulugbek National University of Uzbekistan, Tashkent.

DOI:

https://doi.org/10.55640/

Keywords:

Genetic polymorphism, physical activity, endurance, aerobic and anaerobic abilities, sports genetics, genotype analysis.

Abstract

 This study investigates the significance of vitamin D receptor (VDR) gene polymorphisms — rs2228570 (FokI, T>C) and rs1544410 (BsmI, G>A) — in determining athletic performance among 652 elite athletes representing different sport types. DNA samples were analyzed using Real-Time PCR with allele-specific fluorescent probes. The T allele of VDR rs2228570 was associated with enhanced aerobic metabolism and endurance, whereas the G allele of VDR rs1544410 was prevalent among athletes in speed- and strength-based sports, indicating its importance for high-intensity activities. The findings emphasize the practical value of VDR genotyping for personalized training design, prevention of overtraining, and the evidence-based selection of optimal sports disciplines.

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Published

2026-03-11

Issue

Vol. 5 No. 03 (2026): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

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Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

ASSOCIATION OF VITAMIN D RECEPTOR (VDR) GENE POLYMORPHISMS WITH PHYSICAL PERFORMANCE IN ELITE ATHLETES. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(03), 506-510. https://doi.org/10.55640/

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