MODULATION OF SKIN INFLAMMATION AND ENHANCEMENT OF REGENERATION USING PLANT-DERIVED THERAPEUTICS

Abstract

Skin inflammation and impaired regeneration represent major clinical and pharmaceutical challenges associated with acute wounds, chronic ulcers, burns, and inflammatory dermatoses. In recent decades, increasing attention has been directed toward plant-based therapeutics as multifunctional agents capable of modulating inflammation and stimulating skin repair. Medicinal plants contain a wide spectrum of biologically active compounds, including flavonoids, terpenoids, phenolic acids, polysaccharides, and fatty acids, which act synergistically to regulate cellular and molecular mechanisms involved in skin healing. This article provides an integrated overview of the inflammatory process in the skin, the biological basis of regeneration, and the therapeutic potential of herbal preparations in promoting tissue repair. Emphasis is placed on mechanisms of action, advantages over synthetic drugs, and prospects for the development of modern phytopharmaceutical dosage forms.