CHEMICAL CHARACTERISTICS, IDENTIFICATION, AND PHARMACEUTICAL APPLICATIONS OF BIOACTIVE CONSTITUENTS IN AMARANTHUS CAUDATUS AND AESCULUS HIPPOCASTANUM

Authors

  • Shakirova Nilufar Makhmudovna Lecturer in Pharmaceutical Technology Department of General Subjects Asia International University Bukhara, Uzbekistan

DOI:

https://doi.org/10.55640/

Keywords:

Amaranthus caudatus; Aesculus hippocastanum; bioactive compounds; phenolic acids; flavonoids; saponins; escin; betalains; antioxidant activity; phytochemical analysis; HPLC; LC-MS/MS; spectroscopic identification; pharmaceutical dosage forms; herbal medicine; nutraceuticals; venotonic agents; anti-inflammatory activity; natural antioxidants; plant-based therapeutics.

Abstract

Medicinal plants are essential sources of biologically active compounds (BACs) that possess diverse therapeutic effects. Among these, Amaranthus caudatus (love-lies-bleeding) and Aesculus hippocastanum (horse chestnut) are recognized for their abundance of phenolics, flavonoids, and saponins with significant antioxidant, anti-inflammatory, and vascular-protective properties. This article reviews their major chemical constituents, presents experimental quantitative data, describes modern analytical identification methods, and discusses existing pharmaceutical dosage forms developed from these plants.

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References

1.Li, H. et al. (2024). Comparative Polyphenolic Analysis in Nine Amaranthus Species. Antioxidants, 13(4), 501.

2.D’Amelia, V. et al. (2022). Agronomic and Phytochemical Variation in Amaranthus Accessions. Plant Foods for Human Nutrition, 77(3), 325–336.

3.Müller-Ladner, U. et al. (2020). Pharmacological Potential of Escin from Aesculus hippocastanum. Phytotherapy Research, 34(4), 735–748.

4.Novaković, M. et al. (2021). UHPLC-MS/MS Characterization and Antioxidant Properties of Aesculus Bark Extracts. Molecules, 26(13), 3895.

5.European Medicines Agency (EMA). (2015). Assessment Report on Aesculus hippocastanum L., semen. EMA/HMPC/745582/2013.

6.Patel, D. et al. (2021). Phytotherapeutic and Nutraceutical Potentials of Amaranthus Species. Journal of Functional Foods, 83, 104519.

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Published

2025-11-13

Issue

Vol. 4 No. 10 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

CHEMICAL CHARACTERISTICS, IDENTIFICATION, AND PHARMACEUTICAL APPLICATIONS OF BIOACTIVE CONSTITUENTS IN AMARANTHUS CAUDATUS AND AESCULUS HIPPOCASTANUM. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(10), 731-733. https://doi.org/10.55640/

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