COLD EMULSIFICATION TECHNOLOGY IN THE PRODUCTION OF MEDICINAL OINTMENTS AND ITS ADVANTAGES

Abstract

 This article examines the cold emulsification technology applied in the manufacturing of medicinal ointments (semi-solid dosage forms). Cold emulsification is a technique in which aqueous and oily phases are combined without heating or with minimal thermal exposure. This approach ensures the stability of thermolabile active ingredients, prevents degradation of auxiliary excipients, and reduces energy consumption during production. The study analyzes the technological stages, criteria for selecting emulsifiers, phase compatibility, and the physicochemical characteristics of the final product. The results demonstrate that ointments manufactured by cold emulsification possess enhanced dispersity, uniform consistency, and increased formulation stability.