OBTAINING AND STANDARDIZATION OF A BIOACTIVE SUPPLEMENT WITH DIURETIC EFFECT BASED ON LOCAL PLANT RAW MATERIALS (ON THE EXAMPLE OF BITTER WORMWOOD AND TRIBULUS TERRESTRIS PLANTS)

Abstract

In recent decades, the use of plant-based bioactive supplements has attracted significant attention in pharmaceutical and medical research. Medicinal plants represent an important source of biologically active compounds that can support physiological functions and contribute to the prevention of various diseases. This study analyzes the possibilities of obtaining and standardizing a bioactive supplement with diuretic activity based on local medicinal plant raw materials, particularly bitter wormwood (Artemisia absinthium) and tribulus (Tribulus terrestris). These plants are widely distributed in Central Asia and have long been used in traditional medicine for their pharmacological properties. Scientific literature indicates that both plants contain flavonoids, saponins, essential oils, and other secondary metabolites that exhibit diuretic and anti-inflammatory effects. The study focuses on the analysis of phytochemical composition, technological processing stages, and quality control indicators necessary for standardizing a bioactive supplement derived from these plants. Moisture content, ash content, extractive substances, and flavonoid concentration were considered as the main parameters for standardization. The results of the analysis demonstrate that bitter wormwood and tribulus can serve as promising plant raw materials for the development of natural diuretic supplements. The proposed technological scheme allows preservation of biologically active compounds while ensuring product safety and quality. The findings highlight the potential of local medicinal plants as sustainable resources for the pharmaceutical industry and emphasize the importance of proper standardization in the production of herbal bioactive supplements.