THE EFFECT OF DIBUNOL ON THE LIPID CONTENT IN THE BLOOD SERUM OF RABBITS WITH EXPERIMENTAL ATHEROSCLEROSIS
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Abstract
This study investigates the influence of dibunol (also known as ionol or butylated hydroxytoluene, BHT), an antioxidant compound, on the lipid profile of rabbits with experimentally induced atherosclerosis. Using a high-cholesterol diet to simulate hyperlipidemia and plaque formation, the experiment evaluates how dibunol administration alters key lipid parameters, including total cholesterol, triglycerides, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels in blood serum. The findings suggest that dibunol has a lipid-modulating effect and may contribute to the prevention or attenuation of atherosclerotic changes through its antioxidant properties.
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1.Steinberg, D. (2012). Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime. Nature Medicine, 8(11), 1211–1217.
2.Mikhailidis, D. P., & Elisaf, M. (2018). Lipid-lowering drugs and antioxidant therapy in atherosclerosis. Current Pharmaceutical Design, 14(3), 238–248.
3.Pokrovsky, S. N., & Markin, A. A. (2013). Lipid metabolism and antioxidants. Moscow: Meditsina.
4.Vlasov, A. P., et al. (2015). The effect of dibunol on lipid peroxidation in rabbits with experimental atherosclerosis. Bulletin of Experimental Biology and Medicine, 119(4), 377–380.