THE EFFECT OF PLANT EXTRACT ON BIOCHEMICAL CHANGES IN THE BLOOD PLASMA OF HEPATITIS MODEL RATS
Article Sidebar
Main Article Content
Abstract
This experimental study evaluated the hepatoprotective properties of aqueous and alcoholic extracts prepared from cabbage leaves (Brassica L.) in a model of hepatitis induced by carbon tetrachloride (CCl₄). During the study, the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin in blood plasma, and malondialdehyde (MDA) in liver homogenate were measured. The results demonstrated the effectiveness of cabbage leaf extracts in reducing liver damage and enhancing antioxidant protection.
Downloads
Article Details
Section
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.
How to Cite
References
1.Fahey J. W., Zhang Y., Talalay P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens//Proc. Natl. Acad. Sci. USA. – 1997. – Vol. 94. – P. 10367–10372.
2.Herr I., Büchler M. W. Dietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer//Cancer Treat. Rev. – 2010. – Vol. 36(5). – P. 377–383.
3.Ilbey B., Ozmen O., Orun I. et al. Hepatoprotective effect of plant-derived antioxidants in experimental liver injury models // Journal of Ethnopharmacology. – 2019. – Vol. 236. – P. 172–181.
4.Kwon D. J., Bae Y. S., Ju S. M. et al. Anti-inflammatory effects of sulforaphane on hepatic damage in a murine model//International Immunopharmacology. – 2014. – Vol. 18(2). – P. 276–282.
5.Singh A., Bhat T. K., Sharma O. P. Clinical biochemistry of hepatotoxicity//Journal of Clinical Toxicology. – 2011. – Vol. S4. – P. 001.
6.Исаева А. И., Киселева Т. Л. Лекарственные растения с гепатопротекторной активностью//Фармакогнозия. – М.: ГЭОТАР-Медиа, 2019. – С. 179–185.
7.Климова И. Д., Громова О. А. Антиоксиданты и печеночная патология: современное представление//Вестник восстановительной медицины. – 2020. – № 2. – С. 43–47.