PSYCHOEMOTIONAL STATE OF PATIENTS WITH CORONARY HEART DISEASE AND CHRONIC KIDNEY DISEASE: THE ROLE OF LIPID-LOWERING THERAPY WITH EZETIMIBE
DOI:
https://doi.org/10.55640/Keywords:
Coronary heart disease, chronic kidney disease, psychoemotional state, lipid metabolism, ezetimibe, lipid-lowering therapy, depression, anxiety.Abstract
This article examines the psychoemotional state of patients suffering from coronary heart disease (CHD) and chronic kidney disease (CKD) and evaluates the impact of lipid-lowering therapy with ezetimibe on their emotional well-being. The relationship between lipid metabolism disorders, systemic inflammation, and the development of depressive and anxiety symptoms is explored. Special attention is given to the therapeutic potential of ezetimibe in not only improving lipid profiles but also contributing to the stabilization of psychoemotional status in this vulnerable group. Clinical findings support the hypothesis that comprehensive lipid management is integral to both physical and psychological health outcomes in CHD and CKD patients.
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1.Grundy, S. M., Stone, N. J., Bailey, A. L. 2018 AHA/ACC Guideline on the Management of Blood Cholesterol // Journal of the American College of Cardiology. – 2019. – Vol. 73, № 24. – P. e285–e350.
2.Cannon, C. P., Blazing, M. A., Giugliano, R. P. Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes // New England Journal of Medicine. – 2015. – Vol. 372, № 25. – P. 2387–2397.
3.Baigent, C., Keech, A., Kearney, P. M. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins // The Lancet. – 2005. – Vol. 366, № 9493. – P. 1267–1278.
4.Libby, P. Inflammation in atherosclerosis // Nature. – 2002. – Vol. 420, № 6917. – P. 868–874.
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