NEGLECTED TROPICAL DISEASES IN UZBEKISTAN: A PUBLIC HEALTH REVIEW

Abstract

Background: Neglected Tropical Diseases (NTDs) are communicable infections that disproportionately affect vulnerable populations and contribute to chronic morbidity and socioeconomic loss. Although global attention has focused on Africa and Southeast Asia, NTDs remain under-recognized in Central Asia, including Uzbekistan.

Methods: This narrative review synthesizes available regional evidence and global policy frameworks to examine the epidemiology, challenges, and control strategies of NTDs in Uzbekistan.

Results: The most relevant NTDs in Uzbekistan are soil-transmitted helminths (STH) and cystic echinococcosis (CE). STH infections persist in rural areas with inadequate sanitation, particularly affecting children. CE remains endemic in livestock-breeding regions due to zoonotic transmission involving dogs and intermediate hosts. Additional parasitic infections, such as enterobiasis and hymenolepiasis, are also reported. Major challenges include limited national surveillance data, environmental and socioeconomic risk factors, and low prioritization of chronic parasitic diseases within health systems.

Conclusion: NTDs continue to pose a public health burden in Uzbekistan. Integrated strategies—strengthened surveillance, preventive chemotherapy, improved water and sanitation, veterinary public health measures, and community education—are essential to reduce transmission and align with global elimination goals.