METHODS AND ANALYSIS OF SYNTHESIS OF NEW BIOLOGICALLY ACTIVE SUBSTANCES BASED ON GOSSYPOL

Authors

  • Yarashova Zuhra Akmal qizi, Khakberdiev Shukhrat Mahramovich Jizzakh Polytechnic Institute
  • Kuchkorov Nodir Akbarovich Urgut is a teacher at the Abu Ali ibn Sino Public Health Technical School

DOI:

https://doi.org/10.55640/

Keywords:

gossypol, biologically active substances, synthesis, analytical methods, HPLC, GC, DART-HRMS, UPLC-MS/MS, polyphenol compounds, enantiomers.

Abstract

This article is devoted to the synthesis of new biologically active substances based on gossypol and methods for their analysis. Gossypol is a polyphenol compound found in the seeds, root bark and other parts of the cotton plant, which has a complex chemical structure and a wide spectrum of biological activity. The article discusses the chemical structure, physicochemical properties of gossypol, methods for synthesizing various derivatives based on it, and modern instrumental methods for analyzing these compounds (HPLC, GC, DART-HRMS, UPLC-MS/MS). The biological activity of gossypol derivatives and their prospects for application in medicine, veterinary medicine and agriculture are also analyzed.

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References

1.Wang X., et al. Nanotechnology in drug delivery systems. Bioorganic Chemistry.

2.Adams L.S. Biological activity of gossypol derivatives. Journal of Natural Products.

3.Zhang Y. Gossypol derivatives as potential anticancer agents. European Journal of Medicinal Chemistry.

4.Torchilin V. Nanoparticulate drug delivery systems. Nature Reviews Drug Discovery.

5.Leach A. Molecular Modelling Principles and Applications. Pearson Education.

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Published

2026-03-20

Issue

Vol. 5 No. 03 (2026): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

METHODS AND ANALYSIS OF SYNTHESIS OF NEW BIOLOGICALLY ACTIVE SUBSTANCES BASED ON GOSSYPOL. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(03), 1580-1582. https://doi.org/10.55640/

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