ETHNOPHARMACOLOGY OF CARTHAMUS TINCTORIUS (L.) AND ITS PHARMACOLOGICAL EFFECTS IN MODERN MEDICINE
DOI:
https://doi.org/10.55640/Keywords:
Carthamus tinctorius (safflower),antioxidant, anti-inflammatory, hepatoprotective, antidiabetic, antifibrotic, and cardioprotective properties.Abstract
There are approximately 50,000 to 70,000 medicinal plant species worldwide. Of these, only 6,000–7,000 species are widely utilized as medicinal plants in traditional medicine and the modern pharmaceutical field. One such plant is Carthamus tinctorius (safflower).
Carthamus tinctorius has been used extensively for centuries in the traditional medicine of China, Iran, and other Eastern countries. It has been employed to improve blood circulation, alleviate pain, provide anti-inflammatory effects, and treat various diseases. Consequently, its ethnopharmacology, rooted in historical experience, continues to generate high scientific interest. Modern research has confirmed the pharmacological activities of safflower, including its antioxidant, anti-inflammatory, hepatoprotective, antidiabetic, antifibrotic, and cardioprotective properties. This positions it as a promising source for the development of new medicinal products in contemporary medicine.
Therefore, integrating traditional ethnopharmacological knowledge with modern pharmacology and clinical research is of great relevance for creating new therapeutic agents from the safflower plant and enhancing the efficacy and safety of drugs.
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1.Liu F, Yang XZ, Li FG, Hu J, Cheng RF. Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma renin activity and angiotensin II level. Acta Pharmaceutica Sinica.
2.1992; 27(10): 785-7. PMID: 1293928. 37) Bingzhang W, Minggang Y, Lei P, Zhanjiu Y. The effects of safflower (Carthamus tinctorius) liquor on ischemic degree of cardiac muscle in different infarct regions of experimental myocardial infarction dog. Acta Pharm Sinica. 1978; 14(8): 474-8. 38) .
3.Guimiao W, Yili L. Clinical application of safflower (Carthamus tinctorius). Zhejiang Tradit Chin Med Sci J. 1985; 1: 42-3. 39).
4.Yue W, Luqiu W. A clinical observation on the effect of rheumatic prescription for treatment of rheumatoid arthritis of 50 cases. J Jiangsu Tradit Chin Med. 1990; 11(2): 1-3. 40).
5.Yukun Z. The treatment of thorax rheumatism of 800 cases with milkvetchpeach-safflower, etc. decoction. Liaoning Tradit Chin Med Sci J. 1988; 12(9): 19-20. 41).
6.Yuk TH, Kang JH, Lee SR, Yuk SW, Lee KG, Song BY, et al. Inhibitory Effect of Carthamus tinctorius L. Seed Extracts on Bone Resorption Mediated by Tyrosine Kinase, COX-2 (cyclooxygenase) and PG (prostaglandin) E2. Am J Chin Med. 2002; 30(01): 95-108. doi: 10.1142/S0192415X02000119. 42).
7.Hiramatsu M, Takahashi T, Komatsu M, Kido T, Kasahara Y. Antioxidant and neuroprotective activities of Mogami-benibana (safflower, Carthamus tinctorius Linne). Neurochemical research. 2009; 34(4): 795-805. doi: 10.1007/s11064-008-9884-5.
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