ANTICOAGULANT THERAPY DURING PREGNANCY
DOI:
https://doi.org/10.55640/Keywords:
Anticoagulant therapy, pregnancy, venous thromboembolism (VTE), pulmonary embolism, hypercoagulable state, low molecular weight heparin (LMWH), unfractionated heparin (UFH), warfarin, direct oral anticoagulants (DOACs), thrombophilia, Factor V Leiden mutation, prothrombin gene mutation, placental insufficiency, maternal morbidity, maternal mortality, thrombosis prevention, anti-Xa monitoring, postpartum thrombosis, obstetric complications.Abstract
Pregnancy is a complex biological process accompanied by significant physiological changes in a woman's body. During this period, the coagulation system becomes markedly activated, increasing the risk of thromboembolic events such as venous thromboembolism and thrombophlebitis. Anticoagulant therapy plays a crucial role in the prevention and treatment of thrombotic complications in pregnant women.
Downloads
References
1.American College of Obstetricians and Gynecologists (ACOG). Thromboembolism in pregnancy. Practice Bulletin No. 196. Obstet Gynecol. 2018;132(1):e1–e17.
2.Royal College of Obstetricians and Gynaecologists (RCOG). Reducing the risk of venous thromboembolism during pregnancy and the puerperium. Green-top Guideline No. 37a. London: RCOG; 2015 (updated guidance).
3.World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience. Geneva: WHO; 2016.
4.American Society of Hematology. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv. 2018;2(22):3317–3359.
5.Bates SM, Greer IA, Middeldorp S, et al. VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e691S–e736S.
6.European Society of Cardiology (ESC). ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J. 2018.
7.James AH. Venous thromboembolism in pregnancy. Arterioscler Thromb Vasc Biol. 2009;29(3):326–331.
8.National Institute for Health and Care Excellence (NICE). Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. NICE guideline. London; 2020.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.
