CHEMICAL-TOXICOLOGICAL ANALYSIS OF PREGABALIN (LYRICA) IN BIOLOGICAL FLUIDS USING A GAS CHROMATOGRAPH (CRYSTALLUX-4000M)
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Abstract
This article presents a detailed methodological approach to the chemical-toxicological analysis of pregabalin (commercially known as Lyrica) in biological fluids using the gas chromatographic system CrystalLux-4000M. Due to pregabalin’s increasing misuse and inclusion in the list of psychotropic substances in many countries, the need for precise, sensitive, and reliable analytical methods is more pressing than ever. The article describes the procedures for sample preparation, extraction techniques, chromatographic conditions, and identification parameters for pregabalin in fluids such as blood plasma and urine. It also highlights the analytical advantages of the CrystalLux-4000M, particularly its thermal stability, high resolution, and applicability in forensic and clinical toxicology.
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References
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