CHEMICAL PROFILING OF FLOWERS FROM THE PAULOWNIA TOMENTOSA × P. FORTUNEI HYBRID (SHAN-TONG) GROWN IN UZBEKISTAN (FERGANA VALLEY)

Abstract

Recent reviews and primary studies show that Paulownia flowers are rich in flavonoids (including prenylated/C-geranylated types), phenylpropanoid glycosides, terpenoids, lignans/iridoids, polysaccharides, and volatile components. For the hybrid Shan-Tong (P. tomentosa × P. fortunei), steam-distilled flower oil contains >30 constituents with lanostane-type derivatives predominating; in P. fortunei flowers, newly described C-geranylated flavonoids (paulownione D–G) have been isolated and structurally confirmed. Building on these advances, we propose a harmonized sampling–extraction–fractionation–identification workflow (GC-MS, HPLC-DAD-MS/MS, HR-MS, and 1D/2D-NMR) tailored to Uzbekistan’s Fergana Valley. We also outline testable hypotheses on climate-driven variation and provide a 6-month workplan from field sampling to manuscript.