IMMUNOHISTOCHEMICAL STUDY OF UTERINE FIBROIDS: NEW APPROACHES TO DIAGNOSIS AND TREATMENT

Authors

  • Natalya Suratovna Nadyrkhanova,Asel Muratkizi Parmanova Republican Specialized Scientific and Practical Medical Center for Maternal and Child Health Resident in Endovisual and Aesthetic Gynecology.,Research Intern, Republican Specialized Scientific and Practical Medical Center for Maternal and Child Health, Tashkent, Republic of Uzbekistan

DOI:

https://doi.org/10.55640/

Keywords:

uterine myoma, leiomyoma, immunohistochemistry, hormonal receptors, personalized medicine, gynecological oncopathology, diagnosis and treatment.

Abstract

Uterine fibroids remain one of the most common benign tumors in women of reproductive age, often associated with severe clinical symptoms and decreased quality of life. In recent years, particular attention has been paid to the molecular biological aspects of fibroid pathogenesis, facilitating the development of personalized treatment approaches. Immunohistochemical examination of fibroid tissue allows us to identify the expression of key protein markers, including hormonal receptors (estrogen and progesterone), proliferation markers, apoptosis, and angiogenesis. These data enable more accurate tumor classification, prognosis, and selection of the most effective therapeutic strategy. This article discusses the current capabilities of immunohistochemistry in the diagnosis and treatment of uterine fibroids, as well as prospects for integrating this method into clinical practice.

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References

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3.Ono, M., et al. (2019). Immunohistochemical expression of hormone receptors and proliferation markers in uterine leiomyoma. Human Pathology, 85, 35–42. https://doi.org/10.1016/j.humpath.2018.11.004

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Published

2025-10-07

Issue

Vol. 4 No. 9 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

IMMUNOHISTOCHEMICAL STUDY OF UTERINE FIBROIDS: NEW APPROACHES TO DIAGNOSIS AND TREATMENT. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(9), 35-38. https://doi.org/10.55640/

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