ROLE OF PHARMACOGENOMICS IN PERSONALIZED DRUG THERAPY: ADVANCES IN MODERN PHARMACY
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Abstract
The integration of pharmacogenomics into pharmaceutical sciences has opened new possibilities for individualized treatment, reducing adverse drug reactions and improving therapeutic efficacy. This study evaluates the impact of genetic profiling on drug metabolism, dosing strategies, and personalized pharmaceutical care. A systematic review of seventy clinical and experimental studies published between 2014 and 2024 was conducted, analyzing the correlation between genetic polymorphisms and pharmacokinetics in various therapeutic classes. The findings demonstrate that pharmacogenomic-guided dosing reduces adverse effects by up to forty percent and optimizes treatment outcomes in oncology, cardiology, and psychiatry. The results emphasize the necessity of incorporating pharmacogenomic testing into clinical pharmacy practice to achieve precision medicine.
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