ROLE OF PHARMACOGENOMICS IN PERSONALIZED DRUG THERAPY: ADVANCES IN MODERN PHARMACY

Authors

  • Umarova Makhfuza Mirzakarimovna,Giyosova Khabibakhon Isakjonovna Andijan State Medical Institute, Uzbekistan

DOI:

https://doi.org/10.55640/

Keywords:

pharmacogenomics, personalized medicine, drug metabolism, pharmaceutical care, adverse drug reactions.

Abstract

 The integration of pharmacogenomics into pharmaceutical sciences has opened new possibilities for individualized treatment, reducing adverse drug reactions and improving therapeutic efficacy. This study evaluates the impact of genetic profiling on drug metabolism, dosing strategies, and personalized pharmaceutical care. A systematic review of seventy clinical and experimental studies published between 2014 and 2024 was conducted, analyzing the correlation between genetic polymorphisms and pharmacokinetics in various therapeutic classes. The findings demonstrate that pharmacogenomic-guided dosing reduces adverse effects by up to forty percent and optimizes treatment outcomes in oncology, cardiology, and psychiatry. The results emphasize the necessity of incorporating pharmacogenomic testing into clinical pharmacy practice to achieve precision medicine.

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References

1.Relling MV, Evans WE. Pharmacogenomics in the clinic. Nature. 2021;576:343–352.

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Published

2025-07-26

Issue

Vol. 4 No. 6 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

ROLE OF PHARMACOGENOMICS IN PERSONALIZED DRUG THERAPY: ADVANCES IN MODERN PHARMACY. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(6), 439-441. https://doi.org/10.55640/

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