ENDOTHELIAL FUNCTION IN VASCULAR HOMEOSTASIS AND DISEASE PREVENTION
DOI:
https://doi.org/10.55640/Keywords:
Endothelial function; vascular homeostasis; nitric oxide; endothelial dysfunction; cardiovascular disease preventionAbstract
The vascular endothelium is a dynamic and metabolically active organ that plays a central role in maintaining vascular homeostasis. Beyond serving as a passive barrier between blood and tissues, endothelial cells regulate vascular tone, blood flow, hemostasis, inflammation, and metabolic balance through the release of numerous bioactive substances. Endothelial dysfunction is recognized as an early and critical event in the development of cardiovascular and metabolic diseases, including hypertension, atherosclerosis, and diabetes mellitus. This article reviews the physiological functions of the endothelium in vascular homeostasis and highlights its role in disease prevention. Understanding endothelial function provides important insights into cardiovascular health and offers potential targets for preventive and therapeutic interventions.
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