HISTOLOGICAL STRUCTURE AND FUNCTIONAL SPECIALIZATION OF THE LIVER LOBULE
DOI:
https://doi.org/10.55640/Keywords:
liver histology, hepatocytes, liver lobule, portal triad, Kupffer cells, central vein, sinusoidAbstract
The liver is a vital organ with complex structural organization that supports its multifunctional roles in metabolism, detoxification, protein synthesis, and bile production. Histologically, the liver lobule is the fundamental structural and functional unit composed of hepatocytes arranged in plates surrounding a central vein. This study examines the microanatomy of the liver lobule using standard histological staining techniques to highlight the arrangement of hepatocytes, sinusoidal capillaries, Kupffer cells, and portal triads. Particular attention is given to the relationship between histological organization and physiological function. Understanding liver histology is essential for the accurate interpretation of pathological conditions such as hepatitis, cirrhosis, and hepatic neoplasms.
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