THE ROLE OF PUVA THERAPY IN THE TREATMENT OF PSORIASIS

Authors

  • Azizbek Ruzalievich Kamalov Assistant Lecturer, Department of Infectious Diseases and Dermatovenereology Central Asian Medical University (CAMU) Fergana, Uzbekistan

DOI:

https://doi.org/10.55640/

Keywords:

psoriasis, PUVA therapy, phototherapy, psoralen, UVA, dermatology, immune modulation.

Abstract

Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by keratinocyte hyperproliferation and dysregulated immune responses. Despite advances in biologic therapies, phototherapy remains an important treatment modality for moderate-to-severe psoriasis. PUVA therapy (psoralen plus ultraviolet A) is one of the most established photochemotherapy methods used in dermatological practice. It combines a photosensitizing agent (psoralen) with UVA radiation to induce anti-proliferative and immunomodulatory effects on psoriatic lesions. This article reviews the mechanisms of PUVA therapy, its clinical efficacy, indications, safety profile, and its role in modern psoriasis management.

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References

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Published

2026-06-04

Issue

Vol. 5 No. 6 (2026): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

THE ROLE OF PUVA THERAPY IN THE TREATMENT OF PSORIASIS. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(6), 95-98. https://doi.org/10.55640/

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