HYPOTHYROIDISM AND CARDIOVASCULAR PATHOLOGY: RISK FACTORS, EARLY DIAGNOSIS, AND WAYS TO PREVENT COMPLICATIONS
DOI:
https://doi.org/10.55640/Keywords:
hypothyroidism, cardiovascular pathology, cardiovascular risk factors, early diagnosis, thyroid-stimulating hormone, free thyroxine, dyslipidemia, bradycardia, prevention of complications, thyroid dysfunctionAbstract
This article examines the relationship between hypothyroidism and cardiovascular pathology, with particular emphasis on risk factors, early diagnosis, and prevention of complications. The review shows that thyroid hormone deficiency may contribute to dyslipidemia, bradycardia, impaired cardiac function, and a higher burden of cardiovascular risk factors, all of which can worsen patient outcomes if hypothyroidism is not recognized in time. The article also highlights the importance of laboratory confirmation using thyroid-stimulating hormone and free thyroxine for early detection, especially in patients with nonspecific symptoms or pre-existing cardiovascular disease. In addition, the review emphasizes that prevention of cardiovascular complications depends not only on diagnosis itself, but also on adequate long-term treatment and follow-up. Thus, the article supports the view that hypothyroidism should be considered not only as an endocrine disorder, but also as a clinically significant condition in cardiovascular medicine.Downloads
References
1.National Institute of Diabetes and Digestive and Kidney Diseases. Hypothyroidism (Underactive Thyroid). Bethesda, MD: NIDDK; updated 2024. Available from: NIDDK website.
2.American Thyroid Association. Hypothyroidism. Falls Church, VA: American Thyroid Association; available on the ATA patient information portal.
3.American Thyroid Association. Thyroid Function Tests. Falls Church, VA: American Thyroid Association; available on the ATA patient information portal.
4.Ahmed HM, Al-Jawad A, Abdullah AA, et al. Hypothyroidism and Cardiovascular Disease: A Review. Cureus. 2024;16(1):e52512. doi:10.7759/cureus.52512.
5.Baretella O, Razvi S, et al. Associations Between Subclinical Thyroid Dysfunction and Cardiovascular Risk Factors According to Age and Sex. The Journal of Clinical Endocrinology & Metabolism. 2025;110(5):e1315-e1327. doi:10.1210/clinem/dgae860.
Eslatma: web natijasida maqola JCEM 2025 yil may sonida chiqqani va DOI ko‘rsatilgani tasdiqlandi, lekin mualliflar ro‘yxatining to‘liq qismi ochiq snippetda to‘liq ko‘rinmadi.
6.Evron JM, Hummel SL, Reyes-Gastelum D, et al. Association of Thyroid Hormone Treatment Intensity With Cardiovascular Mortality Among US Veterans. JAMA Network Open. 2022;5(5):e2211863.
7.American Thyroid Association. Overtreatment and undertreatment of hypothyroidism with thyroid hormone is associated with increased death from heart disease. Clinical Thyroidology for the Public. 2023;16(2):3-4.
8.Chaker L, Papaleontiou M. Hypothyroidism: A Review. JAMA. 2025 Sep 3.
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