HELICOBACTER PYLORI INFECTION: DIAGNOSTIC APPROACHES, THERAPEUTIC STRATEGIES AND PREVALANCE IN THE POPULATION OF BHUKHARA: A REVIEW ARTICLE
DOI:
https://doi.org/10.55640/Keywords:
Helicobacter pylori, diagnosis, treatment, prevalence, Bukhara, peptic ulcer diseaseAbstract
Helicobacter pylori (H. pylori) infection is one of the most prevalent chronic bacterial infections worldwide and represents a major cause of gastrointestinal morbidity. The organism is strongly associated with chronic gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma, and gastric carcinoma. Despite improvements in diagnostic techniques and therapeutic regimens, eradication remains challenging due to rising antimicrobial resistance and marked regional variation in prevalence. This review summarizes the epidemiology, pathogenesis, clinical manifestations, diagnostic approaches, and treatment strategies for H. pylori, with particular emphasis on its prevalence among the population of Bukhara. Understanding regional epidemiological patterns is essential for optimizing diagnostic and treatment strategies.
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