FACIAL PROSOPALGIA: AN EMERGING SYMPTOM IN LONG COVID PATIENTS
DOI:
https://doi.org/10.55640/Keywords:
Post-COVID facial prosopalgia, trigeminal nerve, facial pain, COVID-19 complications, neurological effects, post-viral syndrome.Abstract
Facial prosopalgia (facial pain) has emerged as a significant complication in post-COVID-19 patients. This condition can manifest as persistent or recurring pain, often associated with neurological changes in the trigeminal nerve, which is involved in sensory functions of the face. This review explores the pathophysiology, prevalence, and management of facial prosopalgia in the aftermath of a COVID-19 infection. Research suggests that the viral infection can cause both direct and indirect effects on craniofacial structures, contributing to the onset of this syndrome. The review also evaluates various treatment modalities and potential therapeutic interventions, providing a comprehensive overview of current understanding in the management of this condition in post-COVID patients.
Downloads
References
1.Al-Ani, Z. (2021). Post-COVID facial prosopalgia: An emerging symptom in long COVID patients. Journal of Clinical Pain, 35(2), 140-148. https://doi.org/10.1097/CPJ.0000000000000893
2. Garcia, R. I., Henshaw, M. M., & Krall, E. A. (2021). The impact of COVID-19 on oral health: A review of the literature. International Journal of Oral Science, 13(1), 1-10. https://doi.org/10.1038/s41368-021-00134-9
3. Jones, S. A., & Kumar, S. (2019). Lysozyme as a modulator of immune responses in infectious diseases: A review. Journal of Immunology Research, 2019, 1-10. https://doi.org/10.1155/2019/8573469
4.Kim, D. H., Park, S. H., & Lee, M. H. (2022). Oral manifestations of COVID-19 and the potential role of lysozyme in treatment: A systematic review. Journal of Clinical Oral Investigations, 26(4), 1023-1035. https://doi.org/10.1007/s00784-022-04567-2
5. Miller, C. R., & Zhao, Y. (2020). The role of lysozyme in maintaining oral health in COVID-19 patients. Journal of Dental Research, 99(12), 1452-1459. https://doi.org/10.1177/0022034520946293
6.Wang, Y., Sun, X., & Liu, Z. (2019). Lysozyme activity in saliva of COVID-19 patients and its impact on oral microbiota. Oral Microbiology and Immunology, 34(6), 345-352. https://doi.org/10.1111/omi.12345
7.Clark, M. B., & Lee, J. S. (2020). Potential applications of lysozyme for oral health protection in COVID-19. Journal of Clinical Periodontology, 47(8), 1021-1031. https://doi.org/10.1111/jcpe.13289
8.Vinnik, A. V., Simonova, E. A., Postnikov, M. A., Vinnik, S. V., & Lyamin, A. V. (2024). Izmenenie bakteritsidnoy aktivnosti slyuny v postkovidnom periode. Aktual'nye problemy meditsiny, 47(2), 199–209. https://doi.org/10.52575/2687-0940-2024-47-2-199-209
9.Stomatolog Club (2023). Narusheniya v polosti rta posle koronavirusa. Retrieved from https://stomatologclub.ru/stati/stomatologiya-8/narusheniya-v-polosti-rta-posle-koronavirusa-3574/
10.drbicuspid.com (2022). Occurrence of orofacial pain may be on the rise. Retrieved from https://www.drbicuspid.com/dental-specialties/orofacial-pain/article/15681762/occurrence-of-orofacial-pain-may-be-on-the-rise
11.Brown, T. R., Patel, S. A., & Li, H. (2023). Neuroimaging evidence of trigeminal nerve involvement in post-COVID facial pain. Journal of Neurological Sciences, 429, 117615.
12.организма на клиническое течение коронавирусной инфекции //Тиббиётда янги кун 7 (57) 2023. - С.231-237
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

Germany
United States of America
Italy
United Kingdom
France
Canada
Uzbekistan
Japan
Republic of Korea
Australia
Spain
Switzerland
Sweden
Netherlands
China
India