GENETIC CHARACTERISTICS AND CLINICAL SIGNIFICANCE OF X CHROMOSOME-LINKED DISORDERS

Authors

  • Suyunqulova Shahrizoda Shavkatjon qizi Samarkand State Medical University, Department of Medical Biology and General Genetics, Trainee Assistant

DOI:

https://doi.org/10.55640/

Keywords:

X chromosome, hemophilia, color blindness, Duchenne muscular dystrophy, diagnostics, heredity, gene therapy, genetic counseling.

Abstract

This article discusses the genetic basis of X-linked hereditary diseases, their mechanisms of inheritance, clinical manifestations and relevance. The study analyzes the structure of the X chromosome, the genes located on it and their functional significance in the human body. Also, the genetic mechanisms of X-linked diseases such as hemophilia, Daltonism, Duchenne muscular dystrophy are explained through clinical examples. The article covers modern trends in early detection, genetic counseling and diagnostic methods for X-linked hereditary diseases.

Downloads

Download data is not yet available.

References

1.Alberts, B. et al. Molecular Biology of the Cell. Garland Science, 2022.

2.Lyon, M. F. (1961). Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature, 190(4773), 372–373.

3.Nishonboyev, F.X. Medical Genetics. Samarkand, 2023.

4.NIH – National Human Genome Research Institute (2023). The X Chromosome Fact Sheet. https://www.genome.gov/

5.National Center for Biotechnology Information (NCBI). (2024). X Chromosome – Homo sapiens (human). GenBank Database. https://www.ncbi.nlm.nih.gov/chromosome/x

6.Nurmatov, X. E. (2018). Biology: Genetics Section. Tashkent: O‘qituvchi Publishing.

7.Academy of Sciences of the Republic of Uzbekistan. (2023). Human Genome and Collection of Hereditary Diseases. Tashkent.

8.G‘afurov, A.M. Fundamentals of General Genetics. Tashkent, 2020.

Downloads

Published

2026-01-07

Issue

Vol. 5 No. 01 (2026): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

GENETIC CHARACTERISTICS AND CLINICAL SIGNIFICANCE OF X CHROMOSOME-LINKED DISORDERS. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(01), 170-172. https://doi.org/10.55640/

Similar Articles

11-20 of 483

You may also start an advanced similarity search for this article.