DISTINCTIVE CLINICAL FEATURES OF HEPATITIS A IN ADOLESCENT GIRLS
Abstract
Background: Hepatitis A virus (HAV) infection remains a significant public health concern, particularly in developing countries. While the clinical manifestations of HAV are well-documented in children and adults, there is a paucity of data focusing specifically on adolescent girls. This study aims to elucidate the distinctive clinical features of hepatitis A in this demographic. Methods: A retrospective observational study was conducted involving 120 adolescent girls aged 10–18 years diagnosed with acute HAV infection between January 2020 and December 2024. Clinical presentations, laboratory findings, and outcomes were analyzed. Data were compared with existing literature to identify unique patterns. Results: The most common symptoms were jaundice (85%), anorexia (78%), and abdominal pain (65%). Laboratory findings revealed elevated alanine aminotransferase (ALT) levels averaging 1,500 IU/L and aspartate aminotransferase (AST) levels averaging 1,200 IU/L. Notably, 10% of patients exhibited atypical manifestations such as cholestatic hepatitis. The recovery rate was 98%, with no mortality reported. Conclusions: Adolescent girls with HAV infection present with clinical features similar to the general pediatric population; however, a subset may experience atypical manifestations. Awareness of these distinctive features is crucial for timely diagnosis and management.
Keywords
Hepatitis A, Adolescent Girls, Clinical Features, Liver Enzymes, Cholestatic HepatitisHow to Cite
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