MORPHOMETRIC CHANGES IN RATS FOLLOWING ALCOHOL (ETHANOL) INTOXICATION — A CONCISE REVIEW
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Abstract
Alcohol (ethanol) exposure produces reproducible morphometric and histological alterations in multiple rat organs. The most consistently reported changes include dendritic and spine loss in vulnerable brain regions (hippocampus, cortex), hepatocyte degeneration with steatosis and fibrosis, reduced seminiferous tubule area and impaired spermatogenesis, and structural remodeling in kidneys and salivary glands. This review summarizes quantitative and qualitative morphometric findings from experimental rat models of acute, intermittent and chronic ethanol exposure, highlights common measurement approaches, and provides representative references for each organ system.
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References
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