PATHOPHYSIOLOGICAL AND CLINICAL ASPECTS OF LIVER CIRRHOSIS

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Published: 2025-10-08
DOI: https://doi.org/10.55640/
Keywords:
liver cirrhosis, portal hypertension, fibrosis, hepatocellular carcinoma, pharmacological therapy

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 Dr.A.Victor Simmon
Independent researcher of medical centre in Sochi, Russian

Abstract

Liver cirrhosis is a progressive and irreversible chronic disease characterized by fibrosis, architectural distortion, and regenerative nodules. It represents the final common pathway of many chronic liver injuries, including viral hepatitis, alcohol abuse, and metabolic disorders. The pathophysiological changes of cirrhosis lead to complications such as portal hypertension, hepatic encephalopathy, and hepatocellular carcinoma. This article reviews the underlying mechanisms, clinical features, and pharmacological management strategies associated with cirrhosis. By integrating evidence from clinical and experimental studies, the paper highlights the challenges and therapeutic opportunities in addressing this major global health problem.

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Issue

Vol. 4 No. 9 (2025): Journal of Multidisciplinary Sciences and Innovations

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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

PATHOPHYSIOLOGICAL AND CLINICAL ASPECTS OF LIVER CIRRHOSIS. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(9), 113-115. https://doi.org/10.55640/

References

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5.Jalan, R., & Williams, R. (2016). Acute-on-chronic liver failure: pathophysiological basis of therapeutic options. Blood Purification, 42(2), 99–108.

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