NON-ALCOHOLIC FATTY LIVER DISEASE: CLINICAL FEATURES, DIAGNOSIS, AND MANAGEMENT STRATEGIES

Authors

  • Umarova Mahliyo Abdusalom qizi ,Inomjonova Gulyuz Baxtiyorjon qizi Tashkent International University of Chemistry, Namangan Branch

DOI:

https://doi.org/10.55640/

Keywords:

hepatology, NAFLD, NASH, liver fibrosis, obesity, metabolic syndrome

Abstract

Non-alcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disorder worldwide, strongly associated with obesity, metabolic syndrome, and type 2 diabetes mellitus. Its progression from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma underscores its clinical and public health importance. This article aims to review the clinical features, diagnostic methods, and management strategies for NAFLD within the context of modern hepatology.

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References

1. Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease. Hepatology. 2018;67(1):328–357.

2. EASL–EASD–EASO Clinical Practice Guidelines for the management of NAFLD. J Hepatol. 2016;64(6):1388–1402.

3. Younossi ZM, Koenig AB, Abdelatif D, et al. Global epidemiology of NAFLD. Nat Rev Gastroenterol Hepatol. 2016;13(6):328–340.

4. Friedman SL, Neuschwander-Tetri BA, Rinella M, Sanyal AJ. Mechanisms of NAFLD development and therapeutic strategies. Nat Med. 2018;24(7):908–922.

5. Rinella ME. Nonalcoholic fatty liver disease: A systematic review. JAMA. 2015;313(22):2263–2273.

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Published

2025-09-20

Issue

Vol. 4 No. 8 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

NON-ALCOHOLIC FATTY LIVER DISEASE: CLINICAL FEATURES, DIAGNOSIS, AND MANAGEMENT STRATEGIES. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(8), 481-484. https://doi.org/10.55640/

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