IDENTIFICATION OF ANEMIA SYNDROME IN URBAN AND RURAL LEUKEMIA PATIENTS IN DYNAMICS FOR 2019-2023
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Abstract
Iron deficiency anemia (IDA) is often associated with various chronic diseases, including oncological and oncohematological diseases (leukemia, multiple myeloma, myelodysplastic syndrome, etc.) (1,4,5). According to the World Health Organization (WHO), about 1.62 billion people on the planet suffer from various pathogenetic variants of anemia. IDA accounts for 80% of all forms of anemia in adults [2,3]. The pathogenesis of anemia in chronic diseases (ACD) is associated with iron metabolism, which changes due to an increase in the level of hepcidin, which inhibits the absorption and recirculation of iron. As a result, iron absorption in the duodenum and small intestine decreases, iron recirculation is impaired [8]. The development of anemic syndrome and iron metabolism in patients with hemoblastoses, and in particular leukemia, have been insufficiently studied and have conflicting opinions (2,3).
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