MODERN GENE EDITING METHODS
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Abstract
This article discusses the theoretical foundations, practical applications, and significance of modern gene editing technologies (CRISPR/Cas9, TALEN, ZFN, and others) in the fields of biology and medicine. The advantages and limitations of these methods are analyzed in relation to the treatment of genetic diseases, the improvement of crop varieties, and the optimization of animal breeding.
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References
1.Doudna, J.A., & Charpentier, E. (2014). The new frontier of genome engineering with CRISPR–Cas9. Science, 346(6213), 1258096.
2.Barrangou, R., & Doudna, J. (2016). Applications of CRISPR technologies in research and beyond. Nature Biotechnology, 34(9), 933–941.
3.Carroll, D. (2011). Genome engineering with zinc-finger nucleases. Genetics, 188(4), 773–782.
4.Joung, J.K., & Sander, J.D. (2013). TALENs: a widely applicable technology for targeted genome editing. Nature Reviews Molecular Cell Biology, 14(1), 49–55.
5.Zetsche, B. et al. (2015). Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell, 163(3), 759–771.