PREVENTION OF ACUTE INTESTINAL INFECTIONS
Abstract
Acute intestinal infections – commonly manifesting as acute gastroenteritis with diarrhea and vomiting – remain a significant global public health challenge. These infections are caused by a variety of pathogens (viruses, bacteria, parasites) and disproportionately affect young children and vulnerable populations. Worldwide, they contribute to high morbidity and are among the leading causes of mortality in children under five. Transmission occurs via the fecal-oral route, often through contaminated water, food, or person-to-person spread. Notable outbreaks in recent years (such as large cholera epidemics) underscore the ongoing threat in both developing and developed regions. Effective prevention requires a multifaceted strategy. Key measures include ensuring access to safe drinking water, improving sanitation, promoting hand hygiene and food safety practices, and deploying vaccines (like rotavirus and cholera vaccines) where appropriate. Public health interventions – from community education to robust surveillance and outbreak response – are crucial to reduce the incidence of acute intestinal infections. This article reviews the epidemiology and transmission of these infections, examines recent outbreaks, and highlights evidence-based preventive strategies that can substantially reduce the burden of acute intestinal infections globally.
Keywords
Acute intestinal infections, prevention, water sanitation, hygiene, vaccination, food safety, public health interventions, diarrheal diseases, epidemiology, rotavirus, cholera, handwashing, outbreak control, global health.How to Cite
References
1.World Health Organization (2024). Diarrhoeal disease – Key facts and overview. WHO Fact Sheet. Retrieved from WHO website:.
2.Institute for Health Metrics and Evaluation (2024). Diarrheal diseases remain a leading killer for children under 5, adults 70+. IHME News Release, published Dec 18, 2024. (Data from Global Burden of Disease study showing 1.2 million deaths in 2021).
3.World Health Organization (2015). WHO’s first ever global estimates of foodborne diseases. WHO News, Dec 2015. (Report highlights: ~600 million fall ill and 420,000 die annually from unsafe food).
4.World Health Organization (2024). Cholera – Global situation report (Cholera upsurge 2021-present). WHO Emergencies: Cholera Upsurge (updated 30 April 2024). (Noting 44 countries with cholera in 2022, 25% increase from 2021, and high case-fatality rates).
5.WHO/UNICEF (2023). Yemen reports the highest burden of cholera globally. WHO EMRO News, 23 Dec 2024. (Describes Yemen’s 2017–2020 cholera outbreak as the largest in recent history and provides 2024 cholera updates).
6.Wikipedia (2021). 2016–2021 Yemen cholera outbreak (citing UN and WHO sources). (More than 2.5 million cases and 4,000 deaths by Nov 2021; Yemen’s cholera epidemic due to conflict).
7.World Health Organization (2023). Cholera Fact Sheet – Key facts. (Oral cholera vaccine usefulness).
8.Burnett et al. (2017). Global impact of rotavirus vaccination on childhood hospitalizations and mortality. J. Infect. Dis. 215(11). (Rotavirus vaccine associated with 30–50% reduction in diarrhea hospitalizations).
9.Ejemot-Nwadiaro et al. (2021). Hand washing promotion for preventing diarrhoea (Review). Cochrane Database Syst Rev 2021;11:CD004265. (Handwashing can reduce diarrheal episodes by ~30%)
10.Centers for Disease Control and Prevention (2025). Norovirus Outbreaks – Key Points. CDC Norovirus Website, updated Jan 2, 2025. (About 2,500 norovirus outbreaks reported each year in the U.S.)
11.Centers for Disease Control and Prevention (2011). Outbreak of E. coli O104:H4 infections – Europe, 2011. MMWR 60(50): 1693-1696. (Over 4,000 cases in 16 countries from a sprout-related E. coli outbreak)
12.Пулатов, М. Э., and Х. А. Гаффаров. "ЧАСТОТА ВЫЯВЛЕНИЯ АКТИВНОГО ХРОНИЧЕСКОГО ГЕПАТИТА В СРЕДИ НОСИТЕЛЕЙ HbsAg." In Russian-Uzbekistan Conference, vol. 1, no. 1. 2024.
13.Butabayev Yakubjon TuklibayevichDepartment of infectious diseases Andijan State Medical Institute Uzbekistan, Andijan
14.Tuklibayevich, Butabayev Yakubjon. "ETIOLOGY OF ALLERGIC OTITIS." In Russian-Uzbekistan Conference, vol. 1, no. 1. 2024.
15.Джураев, М. Г., and Я. Т. Бутабаев. "ИЗУЧЕНИЕ ЧАСТОТЫ ВЕНОЗНЫХ ТРОМБОЭМБОЛИЙ У ГОСПИТАЛИЗИРОВАННЫХ ПАЦИЕНТОВ С COVID-19." Экономика и социум 11-1 (102) (2022): 1213-1216.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.