THE ROLE OF NEOPTERIN AS A MARKER OF SYSTEMIC AND LOCAL IMMUNE INFLAMMATION OF THE PERIODONTIUM IN PATIENTS WITH RHEUMATOID ARTHRITIS

Authors

  • Axmadaliev N.N., Xodjaeva M.Y., Rejabbaeva N.L. Tashkent State Medical University

DOI:

https://doi.org/10.55640/

Keywords:

rheumatoid arthritis, neopterin , interleukin-6, C-reactive protein, DAS28, periodontitis, oral fluid.

Abstract

This article presents the results of a comparative study of neopterin levels in oral fluid and plasma in patients with rheumatoid arthritis. The relationship between this indicator and the activity of systemic inflammation, the severity of periodontal tissue damage, and clinical and laboratory markers of disease activity (CRP, IL-6, DAS28) is demonstrated. The diagnostic and prognostic value of neopterin determination in oral fluid as a marker of the local immune response is substantiated.

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References

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Published

2025-12-28

Issue

Vol. 4 No. 11 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

THE ROLE OF NEOPTERIN AS A MARKER OF SYSTEMIC AND LOCAL IMMUNE INFLAMMATION OF THE PERIODONTIUM IN PATIENTS WITH RHEUMATOID ARTHRITIS. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(11), 3330-3332. https://doi.org/10.55640/

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