PATHOLOGICAL CHANGES IN ENT ORGANS CAUSED BY SYSTEMIC DISEASES AND DIAGNOSTIC APPROACHES

Authors

  • Djabbarov Navruz Nardjigitovich Assistant Teacher of the Department of Otolaryngology, Tashkent State Medical University

DOI:

https://doi.org/10.55640/

Keywords:

Systemic diseases, ENT pathology, autoimmune disorders, vasculitis, granulomatous tissue, tissue fibrosis, diagnostic imaging, serological markers, histopathology, clinical diagnosis, multidisciplinary management.

Abstract

This review investigates the spectrum of morphological alterations in ENT (ear, nose, throat) tissues induced by systemic diseases, emphasizing modern diagnostic techniques. Systemic conditions such as autoimmune diseases, vasculitis, metabolic disorders, and hematological abnormalities often lead to distinctive tissue changes, including mucosal ulcerations, granulomatous lesions, vascular damage, and fibrosis. Recognizing these pathological features, supported by imaging, serology, and histopathology, enhances early diagnosis, promotes effective treatment strategies, and improves patient care through multidisciplinary collaboration.

Downloads

Download data is not yet available.

References

1.Zhang, Q., & Sun, L. (2023). Recent advances in understanding ENT involvement in systemic autoimmune diseases. Clinical Rheumatology, 42(2), 371–380.

2.Chen, Y., Zhao, J., & Wu, D. (2022). Advances in imaging and diagnostic techniques for ENT manifestations of systemic autoimmune conditions. Autoimmunity Reviews, 21(5), 102998.

3.Lee, M. H., Lee, S. H., & Kim, S. H. (2021). Histopathological features of vasculitis-related ENT lesions: A review of recent cases. Vascular Medicine, 26(3), 209–216.

4.Patel, V., & Aggarwal, R. (2020). Granulomatous inflammation in ENT tissues: Diagnosis and clinical implications in systemic diseases. World Journal of Otorhinolaryngology - Head and Neck Surgery, 6(4), 204–211.

5.Chang, H. Y., & Hwang, S. Y. (2020). Imaging modalities in the assessment of sinonasal involvement in systemic vasculitis. European Radiology, 30(12), 6669–6678.

6.Kumar, S., & Singh, S. (2021). Diagnosis and management of ENT lesions in autoimmune diseases: Recent advances. International Journal of Otolaryngology, 2021, 8830151.

7.Rodriguez, A., & Garcia, E. (2020). Serological biomarkers in systemic diseases affecting ENT tissues: Diagnostic value and limitations. Autoimmunity Reviews, 19(4), 102518.

8.Ahmed, S., & Sharma, A. (2019). Histopathology of granulomatous lesions in the nasal cavity: Correlation with systemic diseases. Histopathology, 75(6), 984–992.

9.Park, C., & Kim, J. (2019). Role of endoscopy in the diagnosis of ENT involvement in systemic vasculitis. Korean Journal of Otorhinolaryngology - Head and Neck Surgery, 62(8), 473–481.

10.Wu, Y., & Jiang, Q. (2018). MRI features of sinonasal granulomatous diseases related to systemic conditions. American Journal of Neuroradiology, 39(2), 278–283.

11.Saito, H., & Tanaka, Y. (2018). Tissue biopsy in the diagnosis of systemic disease-related ENT lesions: Procedural considerations and pitfalls. Diagnostic Histopathology, 24(10), 448–454.

12.Lee, J. M., & Kim, K. S. (2017). Diagnostic value of serology and histopathology in ENT lesions associated with systemic vasculitis. Lupus, 26(11), 1158–1165.

13.Verma, R., & Sharma, G. (2017). Imaging features of systemic autoimmune diseases affecting ENT structures. Insights into Imaging, 8(3), 341–354.

14.Kim, H., & Lee, S. (2016). Advances in the management of granulomatous and vasculitic ENT lesions. Current Opinion in Otolaryngology & Head and Neck Surgery, 24(3), 187–194.

Downloads

Published

2025-11-25

How to Cite

PATHOLOGICAL CHANGES IN ENT ORGANS CAUSED BY SYSTEMIC DISEASES AND DIAGNOSTIC APPROACHES. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(10), 1913-1916. https://doi.org/10.55640/

Similar Articles

1-10 of 3334

You may also start an advanced similarity search for this article.