BIOLOGICAL ACTIVITY OF QUATERNARY AMMONIUM SALTS DERIVED FROM AROMATIC TERTIARY AMINES

Authors

  • Arziqul Panjiyev,Baxtiyor Bo‘rixonov,Iskandar Allaberdiyev Karshi State Technical University,Associate Professor (PhD), Department of Inorganic Chemistry, Karshi State University,Research Specialist, Uzbekistan GTL LLC

DOI:

https://doi.org/10.55640/

Keywords:

Pyridine, chitosan, esters of monochloroacetic acid, DMF, ethanol, acetone, temperature, IR, NMR.

Abstract

 Reactions between pyridine and certain esters of monochloroacetic acid were carried out to obtain quaternary ammonium salts. As a result of these reactions, a quaternary ammonium salt of pyridine was synthesized. The optimal reaction conditions were studied, and the yields of the resulting salts were calculated. Although chitosan is known for its high biological activity, its limited solubility in water restricts its range of applications. Therefore, the synthesis of quaternary ammonium salts based on chitosan is considered an important reaction. A novel quaternary ammonium salt of chitosan was synthesized using the quaternary ammonium salt of pyridine. The resulting cationic chitosan derivative exhibited antibacterial properties. The synthesized compounds were analyzed using physicochemical methods, including IR and NMR spectroscopy. The results confirmed the formation of the quaternary ammonium salt of chitosan.

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Published

2025-08-14

Issue

Vol. 4 No. 7 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

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Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

BIOLOGICAL ACTIVITY OF QUATERNARY AMMONIUM SALTS DERIVED FROM AROMATIC TERTIARY AMINES. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(7), 250-256. https://doi.org/10.55640/

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