MODERN TREATMENT OF HERPES VIRUS INFECTION AND PROBLEMS OF RESISTANCE TO ANTIVIRAL DRUGS

Authors

  • Abdurakhmonova K.R., Dusiyorova M.S. Assistant of the Department of Microbiology, Virology and Immunology, TDTU,Student of the 1st Faculty of Medicine, TDTU

DOI:

https://doi.org/10.5281/zenodo.20514387

Keywords:

Herpes simplex virus, HSV-1, HSV-2, antiviral therapy, acyclovir, valacyclovir, famciclovir, antiviral resistance, latent infection, relapse, CRISPR-Cas9, therapeutic vaccines, immunomodulation, epigenetic therapy, mRNA vaccines, herpetic encephalitis, neonatal herpes

Abstract

 This article comprehensively analyzes modern treatment methods for infections caused by Herpes simplex virus (HSV-1 and HSV-2), the problem of antiviral drug resistance, and promising therapeutic approaches. Herpes infection is one of the most widespread chronic viral diseases worldwide, characterized by the lifelong persistence of the virus in nerve ganglia in a latent state, which significantly complicates complete eradication of the infection. The article discusses the mechanisms of action, clinical efficacy, and principles of use of major antiviral drugs such as acyclovir, valacyclovir, and famciclovir, as well as issues related to the emergence of resistant viral strains. In addition, modern scientific data on immunomodulators, therapeutic vaccines, mRNA technologies, CRISPR-Cas9 genome editing systems, epigenetic regulation, and novel treatment strategies based on natural antiviral compounds are presented.

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References

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Published

2026-06-02

Issue

Vol. 5 No. 6 (2026): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

MODERN TREATMENT OF HERPES VIRUS INFECTION AND PROBLEMS OF RESISTANCE TO ANTIVIRAL DRUGS. (2026). Journal of Multidisciplinary Sciences and Innovations, 5(6), 13-18. https://doi.org/10.5281/zenodo.20514387

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