SALIVA-BASED BIOMARKERS FOR EARLY DETECTION OF ORAL CANCER.
DOI:
https://doi.org/10.55640/Keywords:
saliva biomarkers, oral cancer, early detection, non-invasive diagnostics, personalized medicine.Abstract
This study investigates the potential of saliva as a non-invasive diagnostic medium for the early detection of oral cancer [1, 2]. Recent research has identified several molecular biomarkers in saliva, including proteins, nucleic acids, and metabolites, that show high sensitivity and specificity for oral squamous cell carcinoma [3, 4]. Saliva-based diagnostics provide advantages over traditional methods by being patient-friendly, cost-effective, and easily repeatable, which facilitates early detection and improves clinical outcomes [2, 5]. This research emphasizes the importance of integrating salivary biomarker analysis into routine oral cancer screening programs and highlights future prospects for personalized, non-invasive diagnostics [1, 3].
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References
1.Zhang, A., Sun, H., Wang, X., Han, Y., & Wang, P. (2016). Salivary biomarkers in oral cancer detection. Clinical Chimica Acta, 444, 80–86.
2.Yakob, M., Sethi, S., & Prakash, S. (2019). Saliva as a diagnostic tool for oral cancers. Journal of Oral Biology and Craniofacial Research, 9(4), 318–323.
3.Liao, Y., & Wong, D. T. (2016). Saliva: A novel tool for oral cancer diagnosis. Oral Oncology, 59, 47–54.
4.Lee, Y. H., & Wong, D. T. (2009). Saliva: An emerging biofluid for early detection of diseases. American Journal of Dentistry, 22(4), 241–248.
5.Nagler, R. M. (2009). Saliva as a tool for early detection of oral cancer: Current state and future perspectives. Oral Oncology, 45(5), 401–408.
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