WOLFRAM (DIDMOAD) SYNDROME: A FAMILIAL CLINICAL CASE WITH LITERATURE REVIEW

Authors

  • Rakhmonberdieva M.B. Tashkent State Medical University

DOI:

https://doi.org/10.55640/

Abstract

This article presents an extended familial clinical case of Wolfram (DIDMOAD) syndrome with an in-depth literature review, discussion of genetic mechanisms, and therapeutic perspectives. Wolfram syndrome is a rare hereditary disorder characterized by the combination of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness, along with neurological and endocrine complications. Despite its rarity, the disease has significant clinical relevance due to its diagnostic complexity and poor prognosis. This paper emphasizes the importance of timely diagnosis, interdisciplinary management, and future therapeutic approaches.

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References

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Published

2025-12-16

Issue

Vol. 4 No. 11 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

WOLFRAM (DIDMOAD) SYNDROME: A FAMILIAL CLINICAL CASE WITH LITERATURE REVIEW. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(11), 2005-2007. https://doi.org/10.55640/