APPLICATION OF MONTMORILLONITE IN BENTONITE AS A PHARMACEUTICAL EXCIPIENT IN DRUG DELIVERY SYSTEMS

Authors

  • Erimbatova Dilnoza Nurulla kizi First-year Master's student, Department of Chemistry, Berdaq Karakalpak State University

DOI:

https://doi.org/10.55640/

Keywords:

Montmorillonite, bentonite, drug delivery system, pharmaceutical excipient, controlled release, adsorption, biocompatibility

Abstract

Montmorillonite, a key component of bentonite clays, has attracted significant interest in pharmaceutical sciences due to its unique physicochemical properties. Its high surface area, swelling capacity, and cation-exchange ability make it a promising excipient in drug delivery systems (DDS). This article reviews the role of montmorillonite as a pharmaceutical excipient, highlighting its applications in improving drug stability, controlled release, and bioavailability. The modification of montmorillonite to enhance drug-carrier interactions and its biocompatibility are also discussed.

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References

Alexandre, M., & Dubois, P. (2000). Polymer-layered silicate nanocomposites: preparation, properties and uses of a new class of materials. Materials Science and Engineering: R: Reports, 28(1-2), 1-63.

Wang, X., & Wang, Y. (2014). Montmorillonite as a drug delivery system for controlled release of drugs. Journal of Nanomaterials, 2014, Article ID 524732.

Aguzzi, C., Cerezo, P., Viseras, C., & Caramella, C. (2007). Use of clays as drug delivery systems: possibilities and limitations. Applied Clay Science, 36(1-3), 22-36.

Carretero, M. I., & Pozo, M. (2009). Clay and non-clay minerals in the pharmaceutical industry. Part I. Excipients and medical applications. Applied Clay Science, 46(1), 73-80.

Zhu, J., Chen, L., Zhu, J., & Liu, X. (2016). Montmorillonite-based nanocomposites for drug delivery: Preparation, characterization, and applications. Journal of Drug Delivery Science and Technology, 33, 78-84.

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Published

2025-06-20

Issue

Vol. 4 No. 5 (2025): Journal of Multidisciplinary Sciences and Innovations

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors retain the copyright of their manuscripts, and all Open Access articles are disseminated under the terms of the Creative Commons Attribution License 4.0 (CC-BY), which licenses unrestricted use, distribution, and reproduction in any medium, provided that the original work is appropriately cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

How to Cite

APPLICATION OF MONTMORILLONITE IN BENTONITE AS A PHARMACEUTICAL EXCIPIENT IN DRUG DELIVERY SYSTEMS. (2025). Journal of Multidisciplinary Sciences and Innovations, 4(5), 890-892. https://doi.org/10.55640/

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